(S)-N-BOC-3-HYDROXY PIPERIDINE
(S)-1-Boc-3-hydroxypiperidine
CAS: 143900-44-1
Molecular Formula: C10H19NO3
(S)-N-BOC-3-HYDROXY PIPERIDINE - Names and Identifiers
(S)-N-BOC-3-HYDROXY PIPERIDINE - Physico-chemical Properties
| Molecular Formula | C10H19NO3 |
| Molar Mass | 201.26 |
| Density | 1.107±0.06 g/cm3(Predicted) |
| Melting Point | 34-40 °C |
| Boling Point | 292.3±33.0 °C(Predicted) |
| Flash Point | 110°C |
| Solubility | Soluble in methanol. |
| Vapor Presure | 0.000198mmHg at 25°C |
| Appearance | Powder |
| Color | White to tan |
| pKa | 14.74±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.495 |
| MDL | MFCD04115307 |
(S)-N-BOC-3-HYDROXY PIPERIDINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29339900 |
(S)-N-BOC-3-HYDROXY PIPERIDINE - Reference Information
| Application | (S)-1-tert-butoxycarbonyl-3-hydroxypiperidine is a piperidine derivative and is an important intermediate with a chiral structure. Many piperidine derivatives have many pharmacological activities such as antibacterial, anti-tumor, treatment of Alzheimer's disease and anesthesia, and are also one of the important drugs for the treatment of viral infection (including AIDS) and diabetes. |
| Use | (S)-1-tert-butoxycarbonyl-3-hydroxypiperidine is an important chiral intermediate for the synthesis of ibrutinib. Ibrutinib is an anti-cancer drug for B- cell malignant tumors. It is a newly approved drug for the treatment of lymphoma. Important drug intermediates for the treatment of viral infections (including AIDS) and diabetes |
Last Update：2024-04-09 21:54:55
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